Toxoplasma gondii-specific IgG avidity testing in pregnant women
نویسندگان
چکیده
منابع مشابه
Assessment of toxoplasma IgG avidity test results in pregnant women.
nfection brought about by Toxoplasma gondii (T. gondii), toxoplasmosis, is transmitted to the fetus via the placenta. Infection may progress in the expectant mother totally asymptomatically. However, such infections are particularly significant because of undesired consequences for the fetus. Immunoglobulin G (IgG) avidity tests, which have come into use in recent years, make it possible to dis...
متن کاملIgG Avidity Test for the Diagnosis of Acute Toxoplasma gondii Infection in Early
Background: Toxoplasmosis is well known as an important infection in pregnant women. Although many serologic methods are available, diagnosis of early Toxoplasmosis may be extremely difficult. Objective: To detect the Toxoplasma IgG antibodies developed at the early stage of infection in pregnant women. Methods: 225 pregnant women, who were in the 2nd to 4th month of their pregnancy, enrolled i...
متن کاملComparison of Toxoplasma gondii IgG avidity Architect and Vidas assays with the estimated date of infection in pregnant women
A maternal Toxoplasma gondii infection during pregnancy is a risk for congenital infection through maternal-fetal transplacental transmission. Estimation of the date of infection is of the utmost importance for management and treatment recommendations. In this setting, IgG avidity has been shown to be useful as high avidity rules out an infection dating less than 4 months. The estimated date of...
متن کاملComparison of four commercially available avidity tests for Toxoplasma gondii-specific IgG antibodies.
Toxoplasma infection in pregnant women may cause congenital toxoplasmosis. Diagnosis of infection is based on serological tests aimed at detecting IgM and IgG antibodies against Toxoplasma gondii. However, IgM antibodies are not an accurate marker for discriminating between acute and latent infection. Detection of residual or persistent IgM may occur months or even years after primary infection...
متن کاملCorrelation between specific IgM levels and percentage IgG-class antibody avidity to Toxoplasma gondii.
Toxoplasmosis is an usually asymptomatic worldwide disseminated infection. In its congenital presentation it may lead to abortion or fetal malformations. Antenatal evaluation is considered of paramount importance to identify seronegative women and allow for prophylaxis. Recent improvements in sensitivity of IgM tests has made IgM detection an extremely protracted acute phase marker, and IgG avi...
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ژورنال
عنوان ژورنال: Clinical Microbiology and Infection
سال: 2020
ISSN: 1198-743X
DOI: 10.1016/j.cmi.2020.04.014